Emmy-winning actress Christina Applegate has recently revealed that she has been hospitalized over 30 times since being diagnosed with multiple sclerosis in 2021. In a candid confession on her podcast, ‘MeSsy with Christina Applegate & Jamie-Lynn Sigler,’ the beloved star opened up about her battle with chronic digestive symptoms that have led to severe episodes of diarrhea and vomiting.
Applegate shared that the pain she has endured from these symptoms has been “unimaginable,” leading to numerous hospital visits for treatment. The actress, known for her roles in hit TV shows such as “Married with Children” and “Dead to Me,” has been transparent about her health struggles since announcing her MS diagnosis.
Multiple sclerosis is a chronic autoimmune disease that affects the central nervous system, leading to a variety of symptoms that can range from mild to debilitating. Applegate’s bravery in discussing her ongoing health challenges sheds light on the reality of living with a chronic illness and the importance of seeking proper medical care.
Fans of the talented actress have expressed their support and well wishes for her continued health and healing. Despite the difficulties she has faced, Applegate remains resilient and determined to raise awareness about MS and the impact it has on those who live with it.
As Christina Applegate continues to navigate her journey with multiple sclerosis, her openness and vulnerability serve as an inspiration to others facing similar challenges. Her courage in sharing her story reminds us all of the importance of prioritizing our health and seeking help when needed. The entertainment industry is rooting for Christina as she bravely battles her illness and continues to shine as a talented and beloved actress.
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Video “Christina Applegate Hospitalized 30+ TIMES for Diarrhea, Vomiting Amid MS Battle” was uploaded on 03/20/2025 to Youtube Channel Entertainment Tonight
This poor woman really needs a break! It’s 💔 to hear of her suffering. I know people who have MS but not to this degree. Praying for remission from this dreadful disease. 🙏🏻💔🙏🏻
So? She is getting old. We need to cared more about people can't afford treatments and animals, not this stupid old bag!😊
My thoughts and prayers are with Christina Applegate 🙏🙏
🙏🙏🙏🙏🙏🙏🙌💞
Peaying for christina❤
I hope she pulls through blessings to Christina ❤
It's so weird how I remember before she got sick and was still healthy , she spoke several times about how she was scared that she would get I'll one day, seems like her fear of becoming ill actually came true because she made it by speaking and thinking it for so long..May GOD heal her body and make it work the way it was created to, in Jesus mighty name..Amen
Sending love too you ❤🙏
God bless her and everyone out there with MS ❤🙏🏼
An Israeli study found a 60% increase in MS for those with BI. Sad that not one woman in these comments has mentioned this association. All you can do is pray and hope and feel bad for Christona or anyone else going througj this. Women need to educate themselves. Its beyond pathetic how dumb the US population has become.
My aunt has it and its hard watching her slowly go through it
I'm sorry but you really can't say that her career has lasted for six decades when she's barely over 50. I know that's not the point of the video, but come on, get the facts straight for her sake.
Cristina Applegate is 53 yrs old. How can she have a six decade career….Hhhmmm.
Poor Christina, this life is not worth such suffering at all. Lord hurry your ass up & get back here.
❤
Christina Applegate needs to get in touch with Mikhaila Peterson.
PRAYERS UP 🙏🏾🙏🏾🙏🏾🙏🏾
She is such a remarkable person, I pray that there will be treatments available soon that will help her and others suffering from this devastating disease.
Six decade career?
6 decade career? She is 50!
Blessings to you Christina you have to be your own advocate bc no one else will proud of you
ET is so disgusting for exploiting this.
This poor woman has been through so much 😢 praying for her 🙏
I wonder if she took ozempic🤔
That cant be good for MS
Kudos to Christina for being a tough cookie, facing it head on and being bluntly candid about the effects. . My aunt developed it as a young girl in the 1930s and later suffered and died from it in the 1960s.
I LOVE HER….I always thought she was one of the MOST beautiful women I have ever seen and my heart SHATTERS for her.
I don't know much about her, but this sounds like gastroparesis, like she said. Chronic illness is so, so brutal. It's absurd that we basically have to be our own doctors because ableism is so baked into the medical profession. The majority of physicians would rather call us hysteric and call it a day than put their training to good use. Disgusting.
Having lots of money and medicine, go hand-in-hand for the greed , worked all my life and health care. It’s disgusting it’s disgraceful and it is Criminal. 🤥💰😡💔🌎
Get it together Drat off drugs and no drinking Christina. Be happy Within. Grow yourself spiritually
All my empathy goes to her, I hope that it stops and does not become a regular issue. I am end stage at 45 and I get the same problems, it is a horrible disease MS, I have Lupus which has me at Stage 4, no transplant option I have non alcoholic cirrhosis. I hope that she has some relief soon. She's right, when you are terminally ill and have severe illness this Earth and being here is feels like hell. Huge empathy to her.
Prayers to you Christina. Big fan. ❤
1:35 her six decade career? so how old does that make her?
Not fair ❤. Kelly im 🙏 for you
Sending you so much love ❤️
"It feels pretty damn lonely". That hits really hard. It doesn't matter if you are rich, famous, and talented if you don't have good health. MS is a horrible disease.
I had a friend who put his MS into remission completely after using diatomaceous earth.
Having an ongoing progressive illness is often madness; feeling our control slip away inch by inch is a frustration that's nearly impossible to put into words. So we have humor for that, thankfully. And when humor falls short, we still have love.
She was born in November 1971. ET reporter is a math genius. Six-decade career, sure.
MSer here. Our nerves are damaged. Where? Everywhere. Brain connections are fried. Was diagnosed 8 years ago. Primary progressive. Ive lost count of how many times ive peed or poo’d myself in the last couple years.
I wish I could make it all go away 😢 sending healing vibes ❤
Stop putting her personal information out there. It is tacky how you use her illness as click bait.
My daughter has MS. It’s a horrible disease.